TY - JOUR A2 - Amantini, Consuelo AU - Harrell, Carl Randall AU - Jovicic, Biljana Popovska AU - Djonov, Valentin AU - Volarevic, Vladislav PY - 2020 DA - 2020/11/20 TI - Therapeutic Potential of Mesenchymal Stem Cells and Their Secretome in the Treatment of SARS-CoV-2-Induced Acute Respiratory Distress Syndrome SP - 1939768 VL - 2020 AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for the development of a new coronavirus disease (COVID-19), is a highly transmittable virus which, in just ten months, infected more than 40 million people in 214 countries worldwide.吸入后,含有SARS-COV-2喷雾器深入肺部并造成严重肺炎、浮转器伤害和威胁生命的急性呼吸困难综合症由于没有治疗或预防COVID-19感染和COVID-19ARDS专用药或疫苗,迫切需要一种新的治疗剂支持氧供应并同时有效缓解SARS-COV-2诱发肺炎机敏干细胞由于其强效免疫机能特征,可增加肺中的氧供应并有效缓解持续的肺炎,包括SARS-COV-2诱发ARDS文章中,我们描述分子机制负责以MSC制模免疫细胞,在SARS-COV-2诱导ARDS开发中起致病作用,我们简要概述了已经进行和正在进行的临床研究,这些研究加深了我们对MSCs及其密钥在COVID-19相关ARDS理疗中的潜在治疗作用的了解。SN-2210-7177UR-https://doi.org/101155/2019368DO-10.1155/20199768JF-分析细胞病理PB-HindawiKW-ER