TY - Jour A2 - Chang，在Ho Au - Venyo，Anthony Kodzo-Grey Py - 2015 Da - 2015/11/12 Ti - 前列腺腺体的初级Leiomyosarcoma文献述评 - 485786 VL - 2015 AB - Primary前列腺（PLSOP）的平滑肌肉瘤是罕见的，迄今为止报告少于200例。Plsops患有尿路症状，血尿病和会阴疼痛;可以或可能与先前治疗前列腺腺癌通过放射治疗和荷尔蒙治疗的历史无关;可能会折磨儿童和成年男性。考试可能会揭示良性扩大的前列腺和难以扩大的质量。可以通过前列腺标本中的主轴形癌细胞的组织学检查结果诊断斑块。免疫组织化学染色趋于阳性，CD44，平滑肌肌动蛋白和Calponin，致常阳性阳性，并且有时对角蛋白阳性。它们对PSA，S-100，CD34，CD117和细胞角蛋白产生负面染色。前列腺初级平滑肌肉瘤的细胞遗传学研究可能展示涉及染色体2,3,9,11和19的克隆染色体重排。在整个预后差。 Surgery with or without chemotherapy would appear to be the mainstay of treatment for PLSOPs that are operable, but generally there is no consensus opinion on the best therapeutic approach. Most cases of PLSOPs are diagnosed in an advanced stage of the disease. A global multicenter trial is required to find therapies that would improve the prognosis. SN - 1687-6369 UR - https://doi.org/10.1155/2015/485786 DO - 10.1155/2015/485786 JF - Advances in Urology PB - Hindawi Publishing Corporation KW - ER -