TY -的A2 Trojano路易吉盟——Canesi,玛格丽塔非盟- Lavolpe,莎拉盟——Cereda Viviana AU - Ranghetti亚历山德拉盟——大音乐家,罗伯托盟——Pezzoli Gianni AU - Rusconi,玛丽亚·路易萨PY - 2020 DA - 2020/11/27 TI -轻度躁狂、抑郁、心境愉快:新证据在帕金森病SP - 5139237六世- 2020 AB -该领域相关情绪障碍的帕金森病(PD)是支离破碎的。这群观察性研究的目的是评估情绪的事件是否变更可能出现在不同疾病阶段和验证nonmotor症状是如何进入不同阶段。我们招收了93名帕金森病门诊(三组:毒品naive-DN;没有表现出电动机fluctuations-n-MF;和展示汽车fluctuations-MF)和50名健康对照组。情绪状态是通过内部评估状态量表(ISS)而抑郁症状进行评估通过贝克抑郁Inventory-II (BDI-II) nonmotor症状通过非症状量表(nms),和冲动控制障碍的存在(ICDs)问卷Impulsive-Compulsive障碍的帕金森症(讽刺)。临床和药理数据也被记录下来。情绪状态分布在两组之间没有显著差异。然而,至于情绪状态分布群体内部,在n-MF(47.6%)和MF患者(50%)、(海波)狂热的存在明显高于其他症状。在DN患者中,轻度躁狂显示38.1%的患病率虽然不显著。 At least one ICD was reported in 29.3% of n-MF and 50% of MF patients. In the MF group, a moderate positive correlation between ISS ACTivation subscale scores and the presence of ICDs and compulsive medication use emerged. Finally, MF patients reported higher BDI-II total scores than DN. Our results show that mood alterations in PD, considering both depressive symptoms and mood elevation, are related to the advanced stages of the disease as well as the presence of ICDs, and dopaminergic therapy would not always be able to restore a normal mood condition. SN - 0953-4180 UR - https://doi.org/10.1155/2020/5139237 DO - 10.1155/2020/5139237 JF - Behavioural Neurology PB - Hindawi KW - ER -