TY - Jour Au - Heikhmakhtiar，Aulia K. Au-Lim，Ki M. PY - 2018 DA - 2018/11/14 TI - CRT和LVAD对LBBB和RBBB SP中心电电延迟的综合作用的计算预测 - 4253928VL - 2018 AB - 两种情况报告显示CRT和LVAD的组合使终级心力衰竭患者显着延长QRS间隔。在其中一个报告中，由于心脏功能的恢复，患者的患者删除了LVAD。然而，尚未进行组合装置的量化。本研究旨在计算仅计算CRT的效果或将LVAD与LVAD与左束分支堵塞（LBBB）和右束分支阻塞（RBBB）条件的机电行为。受试者是普通的窦性心律，LBBB，RBBB，LBBB，仅具有CRT-ONL的RBBB，具有CRT + LVAD的LBBB，以及带CRT + LVAD的RBBB。结果表明，CRT-仅缩短了LBBB和RBBB条件下的总电激活时间（吃）分别为20.2％和17.1％。CRT-仅将脑室的总机械激活时间（MAT）和机电延迟（EMD）分别降低21.3％和10.1％。此外，CRT-仅将收缩腺腺苷三磷酸（ATP）消耗量减少5％，左心室（LV）压力增加6％，并在LBBB条件下通过0.2L / min增强心输出（CO）。然而，CRT-ock在RBBB条件下几乎没有影响心室。 Under the LBBB condition, CRT + LVAD increased LV pressure and CO by 10.5% and by 0.9 L/min, respectively. CRT + LVAD reduced ATP consumption by 15%, shortened the MAT by 23.4%, and shortened the EMD by 15.2%. In conclusion, we computationally predicted and quantified that the CRT + LVAD implementation is superior to CRT-only implementation particularly in HF with LBBB condition. SN - 1748-670X UR - https://doi.org/10.1155/2018/4253928 DO - 10.1155/2018/4253928 JF - Computational and Mathematical Methods in Medicine PB - Hindawi KW - ER -