ty -jour a2 -Mayordomo，Jose I. Au -Seegobin，Karan Au -Maharaj，Satish Au -Baldeo -Baldeo，Cherisse au -Shukri -Shukri，Amal Au -Rana，Fauzia N. Py -2017 da -2017/2017/2017/12/03 ti-成人兰格汉细胞组织细胞增多症的侵略性形式：治疗挑战SP -9064326 VL -2017 AB -Langerhans细胞组织细胞增多症（LCH）在成人中很少见。由于再次发生，定期随访是强制性的。一名35岁的男性患有偶然的左骨病变，被诊断出患有LCH。后来，他因髋关节疼痛和疾病传播而成为症状。尽管切除了有症状的iliac病变，但他在细胞押滨和Nivolumab上的进展仍取得了进展，这是通过增加骨痛和其他骨骼对成像的参与而证明的。他切除了下颌病变的切除，然后切除了葡萄碱。他没有疼痛，三个月后在宠物成像上患有稳定的疾病。LCH是一种罕见的肿瘤。为有症状的患者保留治疗，同时观察到无症状患者。 Follow-up is imperative due to the risk of reoccurrence. Despite surgical treatment together with one of the front-line agents for refractory disease, in this case cytarabine, he still had progression of the disease. Furthermore, the trial of nivolumab was of no benefit. This case highlights good response to vinblastine which is previously reported to have good success. No trials are published, and the optimal strategy has yet to be defined. LCH with multiple bony involvement can be aggressive and therapeutically challenging. SN - 2090-6706 UR - https://doi.org/10.1155/2017/9064326 DO - 10.1155/2017/9064326 JF - Case Reports in Oncological Medicine PB - Hindawi KW - ER -