TY -的A2 Lenehan彼得·f . AU - Tetikkurt Seza盟——TaşFaruk AU -埃姆雷,基础非盟- OzsoyŞule AU - Bilece,泽克Tolga PY - 2018 DA - 2018/11/13 TI -重要的中性Emperipolesis鳞状细胞癌SP - 1301562六世- 2018 AB - 53岁男子承认对牙齿移动。大量被CT发现牙齿基地。运行切片的组织病理学显示中度分化鳞状细胞癌。许多完整的中性粒细胞中观察到恶性细胞的细胞质中。病人接受部分上颌骨切除术和双边颈部解剖。重大发现中性emperipolesis切除材料。四个肿瘤复发在头部和颈部区域后续开发。手术和放化疗。最新的肿瘤复发发生在peripharyngeal和后parotideal地区。病人开始pembrolizumab疗法和近乎完整的治疗反应发生。 Pembrolizumab was discontinued due to the adrenal insufficiency and pulmonary tuberculosis that developed as a treatment side effect. Pembrolizumab was commenced again when tumor recurrence occurred. The patient is currently alive with ongoing pembrolizumab and antituberculous treatment. We present this case to remark the presence of a significant neutrophilic emperipolesis in the squamous cell carcinoma of the hard palate and maxilla which is rarely encountered. Emperipolesis may predict tumor behavior and the consequences of immune-modulating treatment response in squamous cell carcinomas of the head and neck in regard to the findings of our case. SN - 2090-6706 UR - https://doi.org/10.1155/2018/1301562 DO - 10.1155/2018/1301562 JF - Case Reports in Oncological Medicine PB - Hindawi KW - ER -