TY - A2的陶菲克Ossama w . AU - Dabrowski杜米尼克AU -席尔瓦,罗伯特·f·盟——Constantinescu迈克尔AU -沙克尔福德,罗德尼·e . AU -克鲁斯肯,内斯特盟——魏,埃里克·x PY - 2020 DA - 2020/12/22 TI -同步发生脾多形性套细胞淋巴瘤和食管腺癌BCL1蛋白质的过度SP - 8888829六世- 2020 AB -同步出现的套细胞淋巴瘤(制程),或中间淋巴细胞淋巴瘤等恶性肿瘤是罕见的。这种情况下目前的诊断,特别是治疗的挑战,使他们特别感兴趣的研究。我们报告一个共时程和一位上了年纪的男性患者的食管肿瘤。形态、肿瘤属于脾多形性的恢复期,并发食管腺癌的发生。多形性的制程模拟弥漫性大B细胞淋巴瘤(DLBCL),但缺乏大centroblast——或者immunoblast-like细胞。奇怪的是,这两种肿瘤中细胞周期蛋白D1免疫组织化学。这是一个重要的功能,区分制程病态最亲密的两个实体的鉴别诊断:慢性淋巴细胞白血病和DLBCL,后者地幔细胞不能转变成。lymphoproliferation透露本/ CCND1易位鱼,但食管腺癌仅显示CCND1异倍性没有分裂的信号。自胃肠道(GI)束是一种常见的淋巴结外侵犯参与制程和淋巴瘤的息肉病可呈现胃肠道息肉,足够谨慎区分先进的制程阶段的食管腺癌,转移性腺癌。尽管许多免疫组织化学染色研究,只有BCL1证明肿瘤有部分重叠。 The patient underwent esophagectomy and splenectomy. A subsequent metastatic primary lung squamous cell carcinoma was diagnosed, after which the patient expired. MCL typically presents at an advanced stage and has been deemed incurable with a prognosis of only several years. It is unclear whether the patient succumbed to complications of his MCL or the metastatic squamous cell carcinoma. Furthermore, he was lost to follow-up for a year and only received treatment after his third cancer was diagnosed. We have reviewed previous reports of synchronic mantle cell lymphoma and other solid tumors or hematological malignancies in the literature. SN - 2090-6706 UR - https://doi.org/10.1155/2020/8888829 DO - 10.1155/2020/8888829 JF - Case Reports in Oncological Medicine PB - Hindawi KW - ER -