TY - JOUR A2 - Di Cesare, Paul E. AU - Tamiya, Hironari AU - saabe, Hideaki AU - Yamashita, Katsunari AU - Imura, Yoshinori AU - Wakamatsu, Toru AU - Takenaka，SP - 8873185 VL - 2020以AB -阿霉素为基础的化疗通常用于恶性软组织肉瘤，包括黏液样脂肪肉瘤。然而，在阿霉素治疗无效或失败的情况下，小梁内皮素或丙种球蛋白可对黏液样脂肪肉瘤产生良好的抗肿瘤作用。我们的经验，64岁女性粘液样脂肪肉瘤，谁注意到一个结节在她的左大腿和来我们研究所。在最初的表现，肿瘤直径为18.7厘米，磁共振成像(MRI)显示恶性脂肪瘤与黏液成分。我们建议她接受治疗;不过,她拒绝了。三年后，肿瘤变得更大了，所以她最终决定接受治疗。穿刺活检显示为粘液样脂肪肉瘤。肿瘤大量累及神经血管结构; we thus determined that hip disarticulation was inevitable. Two years later, metastases in the right thigh, left lung, right ileum, and abdominal space were pointed out and chemotherapy was initiated. Adriamycin was unusable due to cardiac dysfunction, so trabectedin was administered; however, the tumors progressed. Eribulin was subsequently started and has been considerably effective for more than 2 years without severe adverse effects. In conclusion, we experienced a case showing the remarkable and long-lasting effect of eribulin against trabectedin-resistant myxoid liposarcoma. SN - 2090-6749 UR - https://doi.org/10.1155/2020/8873185 DO - 10.1155/2020/8873185 JF - Case Reports in Orthopedics PB - Hindawi KW - ER -