TY - Jour A2 - Kuwabara，Hiroko Au - Dabrowski，Dominik Au - Ozluk，ezluk，ezluk，伊斯维亚，Silvia Au - Wei，Eric X. Py - 2020 da - 2020/10/16 Ti - 焦点节段性肾小球粥样硬化前2型乳头状肾脏细胞癌SP - 8811905 VL - 2020 AB - 肾细胞癌（RCC）是成人中主要的肾病恶性肿瘤。在四个一般亚型中，乳头状肾细胞癌（P-RCC）是第二种最常见的并且可以细分为I型，II型和I型和II型的混合物。局灶性节段性肾小球粥样硬化（FSGs）是所有年龄段中最常见的肾小球病变，并且可以被视为平原综合征。通常，RCC众所周知，患有许多静脉抑制综合征，并且肾小球疗法是其中的。很少，RCC和肾小球疗法可能在同一患者中重叠。在这里，我们报告了一名58岁的男性，患有过去的FSG和慢性肾病（CKD），III阶段的患者，他被发现有临床肾脏肿块，后来被诊断为II型P-RCC。组织学显示了具有嗜酸性细胞质的假冒肿瘤细胞，形成乳头状配置和显示坏死区域。先前的FSGS诊断表现出节段性硬化，耐火簇和毛细管膜皱纹。在肾小球病的诊断和恶性肿瘤之间经过了1.5年的时间。 The tumor was found to be at stage TIb. To our knowledge, this may be the first reported case of usual-type FSGS as paraneoplastic glomerulopathy (PG) preceding P-RCC. Because FSGS only sparingly affects the kidney and is a common glomerulopathy in adults, it is reasonable to complete comprehensive diagnostic studies and commence medically necessary treatment, especially in the background of other renal comorbidities. These preexisting comorbidities may be associated with malignancy very early in its course. The probability of RCC-associated paraneoplastic glomerulopathy is low, which means an already incidentally found renal mass may conceal a serpentine paraneoplastic syndrome. A more developed understanding of these manifestations can lead experienced clinicians to suspect and possibly uncover an insidious RCC before it advances. SN - 2090-6781 UR - https://doi.org/10.1155/2020/8811905 DO - 10.1155/2020/8811905 JF - Case Reports in Pathology PB - Hindawi KW - ER -