TY -的A2 -许,蔡Ching盟——Hounoki Hiroyuki盟——信田,Koichiro盟,松井Atsushi AU -时候,舞妓AU -山口,Satoshi AU - Kakeshita,哥打盟,山崎Hidenori盟——小池百合子Tsutomu AU -牧野,Teruhiko盟——托比,滨PY - 2021 DA - 2021/01/07 TI -一个系统性红斑狼疮和Antineutrophil细胞质Antibodies-Associated血管炎重叠综合征SP - 6690658六世- 2021 AB -一个重叠的系统性红斑狼疮(SLE)和Antineutrophil胞质抗体(ANCA)相关血管炎(AAV)是极其罕见的:大约40个病例报告。文献综述表明,他们四十多岁的女性中更常见,同时据报道在69%的情况下。此外,狼疮肾炎和ANCA-associated观察肾小球肾炎肾活检。这份报告提出了一个35岁的女人和一个8个月的历史polyarthralgia承认我们医院。她被诊断出患有系统性红斑狼疮疾病的典型临床表现:多发性关节炎,淋巴细胞减少症,hypocomplementemia,反核和anti-dsDNA抗体和蛋白尿。然而,紫癜四散,antimyeloperoxidase-antineutrophil胞质抗体的效价(MPO-ANCA)高。皮肤活检显示leukocytoclastic血管炎,可怜的免疫复合物沉积。肾活检显示坏死性肾小球肾炎涉及细胞和fibrocellular新月形成沉积IgM和C3c只有在系膜区和外围毛细血管。此外,没有在电子显微镜下观察到的电子致密沉积物。这些病理结果与AAV而不是系统性红斑狼疮。 Therefore, we finally diagnosed the patient with both SLE and microscopic polyangiitis. After treatment with methylprednisolone and intravenous cyclophosphamide pulse therapies, renal function improved and MPO-ANCA levels decreased. In cases of suspected overlap between SLE and AAV, appropriate diagnosis and treatment are important. SN - 2090-6889 UR - https://doi.org/10.1155/2021/6690658 DO - 10.1155/2021/6690658 JF - Case Reports in Rheumatology PB - Hindawi KW - ER -