TY -的A2 -罗斯,迈克尔•AU - Korkmaz Celalettin盟——Demircioglu斯楠PY - 2020 DA - 2020/09/24 TI -协会的嗜中性粒细胞、淋巴细胞和血小板/淋巴细胞比率和血液参数与诊断、阶段,肺外的参与,肺动脉高压,对治疗的反应,患者的预后和结节病SP - 1696450六世- 2020 AB -结节病是一种罕见的疾病,其特征是肉芽肿炎症在受影响的器官,主要在肺部。中性粒细胞/淋巴细胞比率(NLR)和血小板/淋巴细胞比率(PLR)是简单和实用的方法在诊断提供有价值的信息,各种疾病严重程度和预后。在这里,我们旨在调查NLR之间的关系,在结节病PLR和血液参数。这项研究是75年与结节病病人和92个对照组。病人的PLR NLR,血液参数比较与控制。此外,NLR和PLR调查之间的差异在结节病的病人,不同的肺外的参与,肺动脉高压(PH),和之间的自发缓解和治疗没有反应阶段也被评估。NLR和PLR结节病病人明显高于控制。NLR,敏感性,特异性,阳性预测值(PPV)以及阴性预测值(NPV)被发现在68年,61年,58岁的70%,而敏感性,特异性,PPV,和NPV PLR被发现在72年,67年,63年,和74%,分别。在结节病病人,NLR和PLR明显高于在阶段1和阶段2和3比4。之间存在着显著的弱正相关c反应蛋白(CRP)和NLR PLR。 Mean platelet volume (MPV), hemoglobin (Hgb), and mean corpuscular volume (MCV) were lower among patients than controls. A positive moderate correlation was detected between NLR and CD4/CD8 in blood, while there was a strong positive correlation between CD4/CD8 in bronchoalveolar lavage (BAL) and positive moderate correlation between PLR and CD4/CD8 in BAL. High NLR and PLR values were not significantly associated with pulmonary PH, spontaneous remission, response to treatment, and prognosis. The increase in PLR and NLR may be a guide for diagnoses of both sarcoidosis and lung parenchymal involvement. To use these entities as markers, our findings should be supported with prospective studies with larger samples. SN - 1198-2241 UR - https://doi.org/10.1155/2020/1696450 DO - 10.1155/2020/1696450 JF - Canadian Respiratory Journal PB - Hindawi KW - ER -