TY - Jour A2 - Kam,Chak W. Au - Cao,Zanfeng Au - Yang,Zanfeng Au - Liang,Zhanzheng Au - Liang,Ziingyan Au - Cen,Qingyan Au - Zhang,Zuopeng Au - Liang,Hengrui Au - Liu,Rong Au - Zeng,LiangboAu-Xie,Yubao Au - Wang,Youping Py - 2020 DA - 2020/12/04 TI - 易于仰卧位患者急性呼吸窘迫综合征:随机控制试验的META分析SP - 4973878 VL - 2020AB - 该荟萃分析的目的是比较成人急性呼吸窘迫综合征(ARDS)患者的俯卧效果和安全性。从2020年9月开始,系统地搜索了PubMed,Embase和Cochrane库的电子数据库。采用相应的95%置信区间(CIS)的相对风险(RRS)和加权平均差异(WMDS)来计算汇总使用随机效应模型的结果。为最终的Meta分析选择了12种随机对照试验,共招募了共有2264名成人的ARDS。接受俯卧位通风的患者的死亡风险低于接受仰卧通气的人低13%,但这种效果在统计学上没有统计学意义(RR:0.87; 95%CI:0.75-1.00; P.  = 0.055). There were no significant differences between prone and supine position ventilation on the duration of mechanical ventilation (WMD: −0.22; P.  = 0.883) or ICU stays (WMD: –0.39; P.  = 0.738). The pooled RRs indicate that patients who received prone position ventilation had increased incidence of pressure scores (RR: 1.23; P.  = 0.003), displacement of a thoracotomy tube (RR: 3.14; P.  = 0.047), and endotracheal tube obstruction (RR: 2.45; P.  = 0.001). The results indicated that prone positioning during ventilation might have a beneficial effect on mortality, though incidence of several adverse events was significantly increased for these patients. SN - 2090-2840 UR - https://doi.org/10.1155/2020/4973878 DO - 10.1155/2020/4973878 JF - Emergency Medicine International PB - Hindawi KW - ER -