TY -的A2 Tatti Patrizio AU - Verma Neha AU -回历的七月,阿米尔- AU -巴斯,吉尔AU -劳拉,Luis AU -波特,凯尔AU -哈特,菲利普AU -康威尔,达尔文AU -沃什伯恩,w . Kenneth AU -黑色,西尔维斯特AU -王桂萍,克里斯汀盟——孟捧PY - 2020 DA - 2020/12/22 TI -立即术后全胰腺切除术后的胰岛素需求预测代谢的结果可能和胰岛自体SP - 9282310六世- 2020 AB -慢性胰腺炎(CP)是一种进行性疾病,导致最终损失的内分泌和外分泌功能。总胰切除术和胰岛自体(TPIAT)是一种治疗选择CP患者;然而,预测术后代谢的结果仍然是难以捉摸的。在这个单中心回顾性研究中,我们报告pre-TPIAT特点、β细胞功能指标,胰岛产生,post-TPIAT葡萄糖管理数据,进一步了解他们的关系。胰岛产生、血糖水平和胰岛素要求收集术后72小时总共13 TPIAT接受者之间9 - 2013和9 - 2018。此外,他们的血糖控制和基础胰岛素需求在3、6和12个月post-TPIAT进行了分析。所有13个受试者正常基线空腹血糖水平。胰岛中位数产量4882 IEq /公斤(四分位范围3412 - 8987)。平均术后总胰岛素需求3天是0.43户/公斤。Pre-TPIAT基线血糖、胰岛素、c -肽水平与胰岛收益率没有显著相关性。 Similarly, there was no correlation between islet yield and insulin requirement at 72-hour postoperatively. However, there was an inverse correlation between the absolute islet yield (IEq) and insulin requirement at 6 months and 12 months following post-TPIAT. Further analysis of the relationship between 72-hour post-op insulin requirement and insulin requirement at discharge, 3, 6, and 12 months showed a positive correlation. Despite the finding of inverse correlation of islet yield with long-term basal insulin requirement, this study was not able to detect a correlation between the preoperative parameters to postoperative short-term or long-term outcome as noted in other studies. The 72-hour postoperative insulin requirement is a helpful postoperative predictor of patients needing long-term insulin management following TPIAT. This observation may identify a high-risk group of patients in need of more intensive diabetes education and insulin treatment prior to hospital discharge. SN - 2314-6745 UR - https://doi.org/10.1155/2020/9282310 DO - 10.1155/2020/9282310 JF - Journal of Diabetes Research PB - Hindawi KW - ER -