TY -的A2 Biswas Sukla盟——Niyibizi Jean Baptiste盟——Gatera Emmanuel Kamana PY - 2020 DA - 2020/03/27 TI -诊断性能问题2 (HRP-2)之间,疟疾快速诊断测试和Microscopic-Based染色技术诊断疟疾的SP - 5410263六世- 2020 AB -疟疾等提出了一种诊断挑战在大多数热带国家卢旺达。显微镜仍然是诊断疟疾的黄金标准，但它是劳动密集型的，取决于检验者的技能。疟疾快速诊断测试(RDTs)已经发展成为一种简单、方便的显微镜的替代品。这项横断面研究是在卢旺达东部省Kayonza区Rukara卫生中心进行的。在此期间，共有21名疟疾疑似患者在Rukara保健中心就诊^圣2018年6月至7月30日，纳入本研究。对疟疾患者进行HRP-2 RDTs (CareStart™Malaria HRP-2 (Access Bio, Inc.， Somerset, USA))。准备厚涂片并按照建议进行giemsa染色;然后在显微镜下观察并定量报道;RDTs的报告定性(阳性或阴性)。RDTs和厚涂片结果均记录在数据采集表上。本研究共有150名研究参与者，其中女性87名(58%)，男性63名(42%)。该研究中的患者没有接受任何抗疟药物。研究参与者的平均年龄为31.6±12.4岁，大多数参与者年龄在25 - 44岁之间，少数参与者年龄在65岁以上。RDT (HRP-2)的灵敏度为95.0%，而Giemsa显微镜的灵敏度为100%。 The specificity of RDT (HRP-2) was calculated and found to be 59.2%, whereas the specificity of Giemsa microscopy was 100%. Negative and positive predictive values of RDT are 85.4% and 82.7%, respectively. Negative and positive predictive values of Giemsa microscopy were both 100%. According to the results of the current study, the sensitivity, specificity, and both positive and negative predictive values of Giemsa microscopy are higher than those of histidine-rich protein 2-based rapid diagnostic test for malaria. The results obtained in histidine-rich protein 2-based rapid diagnostic test for malaria parasites should be confirmed with tests with high specificity. Further studies should determine the most appropriate type of rapid diagnostic test of malaria diagnosis to be used in combination with Giemsa microscopy. In addition, sensitivity and specificity of RDT (HRP-2) and Giemsa microscopy should be assessed against molecular biology techniques. SN - 1687-9686 UR - https://doi.org/10.1155/2020/5410263 DO - 10.1155/2020/5410263 JF - Journal of Tropical Medicine PB - Hindawi KW - ER -