TY - JOUR A2 - Pecani, Arbi AU - Wang, Zhiyan AU - Wang, Di AU - Wang, Yi PY - 2017 DA - 2017/12/27 TI - Cigarette Smoking and Adipose Tissue: The Emerging Role in Progression of Atherosclerosis SP - 3102737 VL - 2017 AB - Smoking is an established risk factor for atherosclerosis through several underlying pathways. Moreover, in the development of atherosclerotic plaque formation, obesity, defined as excess fat mass accumulation, also plays a vital role in dyslipidemia and insulin resistance. Substantial evidence shows that cigarette smoking induces multiple pathological effects in adipose tissue, such as differentiation of adipocytes, lipolysis, and secretion properties in adipose tissue. Therefore, there is an emerging speculation in which adipose tissue abnormality induced by smoking or nicotine is likely to accelerate the progression of atherosclerosis. Herein, this review aims to investigate the possible interplay between smoking and adipose tissue dysfunction in the development of atherosclerosis. SN - 0962-9351 UR - https://doi.org/10.1155/2017/3102737 DO - 10.1155/2017/3102737 JF - Mediators of Inflammation PB - Hindawi KW - ER -