TY - Jour A2 - 法拉雷斯，卡洛Au - 方，婷春艾 - 吴，玉轩Au - 陈，易亨·奥林，清恒坝，明红PY - 2020 DA - 2020 /10/10 TI - Risk of Dementia in Patients with Depression or Parkinson’s Disease: A Retrospective Cohort Study SP - 8493916 VL - 2020 AB - 背景。本研究旨在阐明帕金森病（Pd）和抑郁症是独立的风险因素还是痴呆症中的协同作用。 方法。新诊断的PD（ N = 1213) patients and control subjects ( N = 4852) were selected from the Taiwan National Health Insurance Research Database from January 2001 through December 2008. Follow-up ended in 2011 with an outcome of dementia occurring or not. This cohort was divided into controls with or without depression, PD only, and PD with depression. The incident rate of dementia and hazard ratio (HR) using Cox’s regression analysis were calculated for each group. 结果。与没有抑郁症的控制相比，痴呆的调整后的HR为3.29（ P. < 0.001 ）在PD仅限组中，2.77（ P. < 0.001 ）在抑郁症组的PD中，1.55（ P. = 0.024 ）在抑郁症中只有群体。痴呆症的入射率为29.2（每1000人 - 年）在PD仅组中，13.2在PD中的抑郁症组。PD对抑郁组痴呆症的影响产生了0.97的HR（ P. = 0.905 ）。 结论。帕金森病是痴呆症的危险因素。相比之下，抑郁症不是PD患者痴呆症的危险因素，尽管它确实充当痴呆症的危险因素。SN - 2090-8083 UR - https://doi.org/10.1155/2020/8493916 Do - 10.1155 / 2020/8493916 JF - 帕金森病PB - Hindawi KW - ER -