tyjour A2 - Agarwal, Manish AU - Malherbe, Corentin AU - Crutzen, Bernard AU - Schrooyen, Jean AU - Caruso, Giovanni AU - Lecouvet, Frédéric AU - Detrembleur, Christine AU - Schubert, Thomas AU - Docquier,Pierre-Louis PY - 2020 DA - 2020/12/10 TI - Assessment of Resection in Bone Tumor Surgery SP - 5289547 VL - 2020 AB -保肢手术现在是骨肿瘤手术的首选程序。为了降低局部复发的风险,获得足够的切缘是至关重要的。获得的切缘必须在术后进行评估,因为当切缘不充分时,它们会影响随后给予的治疗(如手术修正和放疗)。本研究旨在评估MRI与常规组织学相比对肿瘤标本边缘的评估(以建立MRI的可行性),并评估针对狭窄边缘时患者专用仪器的准确性。采用三种方法前瞻性分析12例连续行骨肿瘤切除术的患者的切缘:切除标本的MRI、标本切片的宏观评价和显微镜病理评价。评估分为定性(R0, R1和R2)和定量(距离以mm为单位)。MRI、宏观边缘和显微镜边缘的定性(所有切除均为R0)和定量评估结果相似。安全边界的中位误差为2 mm(有手术引导)和5 mm(没有手术引导)。平均随访3.7年(2.1-5年)未发现局部复发; however, four patients died during the study. In conclusion, MRI is a valuable tool for assessing safe margins. When specimens are not available for pathological assessment (e.g., extracorporeally irradiated autograft or autoclaved autograft), MRI could be used to evaluate margins. In particular, when tumor volume is high, MRI could also help to focus the pathological examination on areas of concern. SN - 1357-714X UR - https://doi.org/10.1155/2020/5289547 DO - 10.1155/2020/5289547 JF - Sarcoma PB - Hindawi KW - ER -