TY - JOUR A2 - Stylianou，安德烈亚斯AU - 科兹洛娃，埃琳娜AU - Chernysh，亚历山大AU - Manchenko，叶卡捷琳娜AU - Sergunova，维多利亚AU - 莫罗兹，尤PY - 2018 DA - 2018年11月19日TI - 深非线性骨生物力学特性1810585 VL - - 2018 AB - 母语RBC膜在正常状态下修改行动SP的变形天然人的红血细胞（红细胞）的膜的能力弯曲进入细胞，以在尺寸上相当的深度与生理变形进行评价。对于这一点，使用原子力显微镜和原子力光谱的方法。Nonlinear patterns of deep deformation (up to 600 nm) of RBC membranes were studied in normal state and under the action of modifiers: fixator (glutaraldehyde), natural oxidant (hemin), and exogenous intoxicator (zinc ions), 体外。The experimental dependences of membrane bending for control RBC (normal) were approximated by the Hertz model to a depth up to 600 nm. The glutaraldehyde fixator and modifiers increased the absolute value of Young’s modulus of membranes and changed the experimental dependences of probe indentation into the cells. Up to some depth H H ž ，力曲线近似由赫兹模式，进行更深入的缺口 H > H H ž ，多项式函数的程度改变时，膜的硬度增加，压痕的模式变成了另外一个不听从赫兹模式。非线性实验依赖性的定量特性，计算用于通过多项式函数近似这些深弯曲RBC膜。SN - 0161-0457 UR - https://doi.org/10.1155/2018/1810585 DO - 10.1155 /一百八十一万○五百八十五分之二千○一十八JF - 扫描PB - Hindawi出版KW - ER -