TY - JOUR A2 - Matsagkas, Miltiadis I. AU - Hazra, Darpanarayan AU - Sen, Indrani AU - Stephen, Edwin AU - Agarwal, Sunil AU - Nair, Sukesh Chandran AU - Mammen, Joy PY - 2015 DA - 2015/09/01 TI - Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT SP - 307879 VL - 2015 AB - Introduction。Elevated factor VIII population in the Indian population has not been studied as a possible risk factor for deep vein thrombosis (DVT). High factor VIII level is considered a predisposing factor for DVT and its recurrence. However it is known to vary between populations and its exact role in the etiopathogenesis of thrombophilia remains unknown. Material and Methods。Factor VIII levels of patients with DVT who had undergone a prothrombotic workup as a part of their workup was compared to normal age matched controls in a 1 : 3 ratio. Results。There were 75 patients with DVT who had undergone a prothrombotic workup in the course of their treatment for lower limb DVT. In these, 64% had levels of factor VIII more than 150 as compared to 63% of normal controls ( p > 0 05 , not significant). Conclusion。高八世在印度人可能不是一个因素ssociated with the same thrombotic risk as seen in the West. We find a variation in the levels of factor VIII with a different “normal” than what is reported in other populations. This needs further study to elucidate the role of factor VIII in the evaluation and treatment of thrombophilia. SN - 2356-7759 UR - https://doi.org/10.1155/2015/307879 DO - 10.1155/2015/307879 JF - Surgery Research and Practice PB - Hindawi Publishing Corporation KW - ER -