TY - JOUR A2 - 奈斯,Halvor AU - 赫格德,阿贾伊AU - 梅农,吉里什AU - 库马尔,维诺德AU - 拉克希米·普拉萨德,G. AU - Kongwad拉克什曼一AU - 奈尔,拉杰什AU - 纳亚克Raghavendra PY - 2020DA - 2020年1月27日TI - 临床资料和自发性脑出血结局的预测从三级医疗中心在印度南部SP - 2192709 VL - 2020 AB -
背景。本文试图以评估之后在南印度人口高血压SICH临床特征和结果的决定因素。这项研究表示最大系列SICH从印度的一个单中心报道。
材料和方法。前瞻性的数据收集和患者SICH分析住进我们之间1中心ST2015年1月31ST十二月2018年分析的变量包括:年龄,性别,合并症,格拉斯哥昏迷评分(GCS)入院,影像学特征,治疗方法和结果在三个月。改良的Rankin评分(MRS)中的溶液用在放电和三个月评估结果。
结果。Our study group of 905 patients included 638 males and 267 females and the mean age at presentation was 58.10 ± 12.76 years. The study group included 523 patients (57.8%) previously diagnosed hypertensive, of whom 36.3% (
ñ
=
190
)为不规则用药。血肿的最常见的位置是基底神经节(478),丘脑(202),叶(106),小脑(61),脑干(31),和初级脑室内出血(27)。继发性脑室扩展被认为在425(47%)患者入院。The mean volume of the clot on admission was 23.45 ± 19.79 ml, and clot progression was seen in only 46 (5.08%) cases. Surgical evacuation through craniotomy was done in 147 (16.8%) patients, and external ventricular drainage (EVD) was placed in 56 (6.2%) patients. Overall 3−month mortality was 30.1% (266 patients). On the last follow up a favorable outcome (mRS 0−3) was observed in 412 (45.53%) patients and a poor outcome (mRS 4−5) in 207 patients (22.87%). Independent predictors of mortality are Age >70 (
p
=
<
0.001
,OR 4.806,95%CI 3.064-7.54),入院GCS <8(
p
=
<
0.001
, OR7.684, 95% CI 5.055#x2013;11.68), and Hematoma volume >30 ml (
p
=
<
0.001
,OR 2.45,95%CI 1.626-3.691)。脑室内出血是一个额外的结果不能很好地预测(
p
<
0.015
,CI 1.105-2.585)。清除术组中降低死亡率,但发病率保持不变。
结论。SICH主要影响相比于西方社会在印度一个年轻的人口。Elderly age, poor GCS on admission, clot volume above 30 ml and intraventricular extension remain the most consistent predictors of death and poor outcome. Further studies are needed to assess the risk of SICH among hypertensive patients and to prognosticate the outcome after SICH using novel predictors, including biomarkers. SN - 2090-8105 UR - https://doi.org/10.1155/2020/2192709 DO - 10.1155/2020/2192709 JF - Stroke Research and Treatment PB - Hindawi KW - ER -